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Latent.Space(@latentspacepod)

🆕Biohub’s Protein World Model: ESMC-6B, ESMFold2, 6.8B proteins, 1.1B structures, antibody design, ...

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🆕Biohub’s Protein World Model: ESMC-6B, ESMFold2, 6.8B proteins, 1.1B structures, antibody design, ...

TL;DR · AI 摘要

Biohub的Protein World Model通过ESMC-6B和ESMFold2处理68亿蛋白质和11亿结构,展示了生物建模可能像语言建模一样扩展,强调稀疏自编码器揭示模型内部生物学。

核心要点

  • Biohub的ESMC-6B和ESMFold2处理68亿蛋白质和11亿结构。
  • ESMFold2在抗体-抗原预测上击败了专用系统。
  • Biohub的5亿美元虚拟生物学计划旨在构建细胞、疾病和生理学的预测模型。

结构提纲

按章节快速跳转。

  1. Biohub的Protein World Model通过ESMC-6BESMFold2处理大量蛋白质和结构数据。

  2. ESMFold2能够从序列中学习蛋白质的结构和功能,并在抗体-抗原预测上优于专用系统。

  3. 模型处理了68亿蛋白质和11亿结构数据,展示了生物建模的扩展潜力。

  4. 稀疏自编码器揭示了模型内部的生物学信息。

  5. Biohub的5亿美元虚拟生物学计划旨在构建细胞、疾病和生理学的预测模型。

思维导图

用一张图看清主题之间的关系。

查看大纲文本(无障碍 / 无 JS 友好)
  • Biohub的Protein World Model

金句 / Highlights

值得收藏与分享的关键句。

#Biohub#Protein Modeling#ESMFold2#ESMC-6B#Virtual Biology
打开原文

@biohub Head of Science @alexrives explains why biology may scale like language modeling, how metagenomics unlocked" / X

Latent.Space on X: "🆕Biohub’s Protein World Model: ESMC-6B, ESMFold2, 6.8B proteins, 1.1B structures, antibody design, SAEs, & the bitter lesson for biology https://t.co/2PGoHjttCS @biohub Head of Science @alexrives explains why biology may scale like language modeling, how metagenomics unlocked" / X

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Image 2

Latent.Space

@latentspacepod

Image 3: 🆕Biohub’s Protein World Model: ESMC-6B, ESMFold2, 6.8B proteins, 1.1B structures, antibody design, SAEs, & the bitter lesson for biology https://latent.space/p/esmfold2

@biohub

Head of Science

@alexrives

explains why biology may scale like language modeling, how metagenomics unlocked the next ESM scaling curve, why protein LMs can learn structure/function from sequence alone, how sparse autoencoders reveal biology inside the model, why ESMFold2 can beat specialized systems on antibody-antigen prediction, and how Biohub’s $500M Virtual Biology Initiative aims to build predictive models of cells, disease, and eventually physiology.

[](https://t.co/2PGoHjttCS)

latent.space ![Image 4: 🔬ESMFold2: The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub Datasets vs. inductive bias, world models, and programmable biology](https://t.co/2PGoHjttCS)

11:07 PM · May 27, 2026

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