--- title: "Demis Hassabis: Agents, AGI & The Next Big Scientific Breakthrough" source_name: "Y Combinator" original_url: "https://www.youtube.com/watch?v=JNyuX1zoOgU" canonical_url: "https://www.traeai.com/articles/5e1fdd9f-4de7-42b5-ba1c-80784094d13f" content_type: "video" language: "其他" score: 0 tags: [] published_at: "2026-04-29T14:00:34+00:00" created_at: "2026-04-30T09:30:47.781337+00:00" --- # Demis Hassabis: Agents, AGI & The Next Big Scientific Breakthrough Canonical URL: https://www.traeai.com/articles/5e1fdd9f-4de7-42b5-ba1c-80784094d13f Original source: https://www.youtube.com/watch?v=JNyuX1zoOgU ## Summary 该链接指向的是一个YouTube视频页面，而非一篇技术文章。内容无法直接提取和评估。 ## Key Takeaways - 该链接指向的是一个YouTube视频页面，而非一篇技术文章 - 内容无法直接提取和评估 ## Content Title: Demis Hassabis: Agents, AGI & The Next Big Scientific Breakthrough URL Source: http://www.youtube.com/watch?v=JNyuX1zoOgU Markdown Content: # Demis Hassabis: Agents, AGI & The Next Big Scientific Breakthrough - YouTube Back [![Image 1](http://www.youtube.com/watch?v=JNyuX1zoOgU)](http://www.youtube.com/ "YouTube Home") Skip navigation Search Search with your voice [](http://www.youtube.com/watch?v=JNyuX1zoOgU) [Sign in](https://accounts.google.com/ServiceLogin?service=youtube&uilel=3&passive=true&continue=https%3A%2F%2Fwww.youtube.com%2Fsignin%3Faction_handle_signin%3Dtrue%26app%3Ddesktop%26hl%3Den%26next%3Dhttps%253A%252F%252Fwww.youtube.com%252Fwatch%253Fv%253DJNyuX1zoOgU&hl=en&ec=65620) [![Image 2](http://www.youtube.com/watch?v=JNyuX1zoOgU)](http://www.youtube.com/ "YouTube Home") [](http://www.youtube.com/watch?v=JNyuX1zoOgU) [](http://www.youtube.com/watch?v=JNyuX1zoOgU) [](http://www.youtube.com/watch?v=JNyuX1zoOgU) [](http://www.youtube.com/watch?v=JNyuX1zoOgU) [Demis Hassabis: Agents, AGI & The Next Big Scientific Breakthrough](http://www.youtube.com/watch?v=JNyuX1zoOgU) [](http://www.youtube.com/watch?v=JNyuX1zoOgU) Tap to unmute 2x [![Image 3](http://www.youtube.com/watch?v=JNyuX1zoOgU)](http://www.youtube.com/watch?v=JNyuX1zoOgU) ## Demis Hassabis: Agents, AGI & The Next Big Scientific Breakthrough Y Combinator 50,272 views 19 hours ago [](http://www.youtube.com/watch?v=JNyuX1zoOgU) Search Copy link Info Shopping ![Image 4](http://www.youtube.com/watch?v=JNyuX1zoOgU) [![Image 5](http://www.youtube.com/watch?v=JNyuX1zoOgU)](http://www.youtube.com/watch?v=JNyuX1zoOgU) If playback doesn't begin shortly, try restarting your device. • You're signed out Videos you watch may be added to the TV's watch history and influence TV recommendations. 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Please try again later. ![Image 6](http://www.youtube.com/watch?v=JNyuX1zoOgU) 0:00 [](http://www.youtube.com/watch?v=JNyuX1zoOgU)[](https://www.youtube.com/watch?v=96jN2OCOfLs "Next (SHIFT+n)") 0:00 / 0:00 Live •Watch full video • Intro • [26:52 Demis Hassabis: We're Three Quarters of the Way to AGI Sequoia Capital 46K views • 18 hours ago Live Playlist ()Mix (50+)](https://www.youtube.com/watch?v=AFpeWo1GTeg)[29:49 Andrej Karpathy: From Vibe Coding to Agentic Engineering Sequoia Capital 150K views • 18 hours ago Live Playlist ()Mix (50+)](https://www.youtube.com/watch?v=96jN2OCOfLs)[2:13:41 How GPT-5, Claude, and Gemini are actually trained and served – Reiner Pope Dwarkesh Patel 80K views • 16 hours ago Live Playlist ()Mix (50+)](https://www.youtube.com/watch?v=xmkSf5IS-zw)[24:02 Humanoid Robots and the Gap Between Hype and Reality | Bloomberg Primer Bloomberg Originals 101K views • 1 day ago Live Playlist ()Mix (50+)](https://www.youtube.com/watch?v=UQZooauU-FQ)[39:58 Ex-Google Exec: How to Position Yourself Now Before the Next AI Phase (2026–2027) | Mo Gawdat Silicon Valley Girl and Mo Gawdat 760K views • 4 weeks ago Live Playlist ()Mix (50+)](https://www.youtube.com/watch?v=E0Q96IKXx6Q)[13:52 Trump’s Totally Unhinged Assault Rifle Pic, Big Night with King Charles & James Comey Vendetta Jimmy Kimmel Live 1M views • 5 hours ago Live Playlist ()Mix (50+)](https://www.youtube.com/watch?v=hYypemF9ULo)[48:04 Princeton Scientist: We Don't Understand AI Dr Brian Keating 19K views • 19 hours ago Live Playlist ()Mix (50+)](https://www.youtube.com/watch?v=6iMiCJHxTww)[45:06 The 7 Most Powerful Moats For AI Startups Y Combinator 164K views • 6 months ago Live Playlist ()Mix (50+)](https://www.youtube.com/watch?v=bxBzsSsqQAM)[32:34 GPT-5.5 vs Claude vs Gemini: The Real Difference Nobody's Talking About AI News & Strategy Daily | Nate B Jones 76K views • 1 day ago Live Playlist ()Mix (50+)](https://www.youtube.com/watch?v=9aIYhjeYxzM)[1:38:36 AI Insider: The Fastest Way To Use AI Agents In Your Business, Content & Life (Open Claw & Claude)The Calum Johnson Show and Allie K Miller 99K views • 2 days ago Live Playlist ()Mix (50+)](https://www.youtube.com/watch?v=cqMpTbTrMW4)[43:29 What happens now that AI is good at math? — the OpenAI Podcast Ep. 17 OpenAI 34K views • 1 day ago Live Playlist ()Mix (50+)](https://www.youtube.com/watch?v=9-TVwv6wtGQ)[32:23 Demis Hassabis: Why AGI is Bigger than the Industrial Revolution & Where Are The Bottlenecks in AI 20VC with Harry Stebbings 314K views • 3 weeks ago Live Playlist ()Mix (50+)](https://www.youtube.com/watch?v=SSya123u9Yk) Sign in to confirm you’re not a bot This helps protect our community. [Learn more](https://support.google.com/youtube/answer/3037019#zippy=%2Ccheck-that-youre-signed-into-youtube) [Sign in](https://accounts.google.com/ServiceLogin?service=youtube&uilel=3&passive=true&continue=https%3A%2F%2Fwww.youtube.com%2Fsignin%3Faction_handle_signin%3Dtrue%26app%3Ddesktop%26hl%3Den%26next%3D%252Fwatch%253Fv%253DJNyuX1zoOgU&hl=en) # Demis Hassabis: Agents, AGI & The Next Big Scientific Breakthrough [![Image 7](https://yt3.ggpht.com/dGyATx87Fp_s1nZvnupUFSnMqbAPZ6nqRby9Esk1m6YE41iBq-9Z8iGoIgHTCT9SiDBUpP2V=s48-c-k-c0x00ffffff-no-rj)](http://www.youtube.com/@ycombinator) [Y Combinator](http://www.youtube.com/@ycombinator) Y Combinator 2.23M subscribers Subscribe Subscribed 1.6K Share Save Download Download 50,272 views 19 hours ago 50,272 views • Apr 29, 2026 Demis Hassabis has had one of the most extraordinary careers in tech. He started as a chess prodigy and video game designer at 17 before getting a PhD in neuroscience and going on to found DeepMind. His lab cracked Go, solved protein structure prediction with AlphaFold, and then gave it away free to every scientist on earth. That work won him the 2024 Nobel Prize in Chemistr…...more ...more How this was made Auto-dubbed Audio tracks for some languages were automatically generated. [Learn more](http://support.google.com/youtube/answer/15569972?hl=en) ## Chapters View all [![Image 8](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Intro #### Intro 0:00](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### [Intro](http://www.youtube.com/watch?v=JNyuX1zoOgU) 0:00 [![Image 9](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Demis Hassabis: From Chess Prodigy to DeepMind #### Demis Hassabis: From Chess Prodigy to DeepMind 0:46](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=46s) #### [Demis Hassabis: From Chess Prodigy to DeepMind](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=46s) 0:46 [![Image 10](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### What’s Missing Before We Get To AGI? #### What’s Missing Before We Get To AGI? 1:48](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=108s) #### [What’s Missing Before We Get To AGI?](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=108s) 1:48 [![Image 11](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Why Memory Is Still Unsolved #### Why Memory Is Still Unsolved 3:36](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=216s&pp=0gcJCREDDuyUWbzu) #### [Why Memory Is Still Unsolved](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=216s&pp=0gcJCREDDuyUWbzu) 3:36 [![Image 12](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### How AlphaGo Shaped Gemini #### How AlphaGo Shaped Gemini 6:14](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=374s) #### [How AlphaGo Shaped Gemini](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=374s) 6:14 [![Image 13](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Why Smaller Models Are Getting So Powerful #### Why Smaller Models Are Getting So Powerful 8:06](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=486s) #### [Why Smaller Models Are Getting So Powerful](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=486s) 8:06 [![Image 14](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### The 1000x Engineer #### The 1000x Engineer 10:46](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=646s) #### [The 1000x Engineer](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=646s) 10:46 [![Image 15](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Continual Learning and the Future of Agents #### Continual Learning and the Future of Agents 12:40](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=760s) #### [Continual Learning and the Future of Agents](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=760s) 12:40 Transcript Follow along using the transcript. Show transcript [![Image 16](http://www.youtube.com/watch?v=JNyuX1zoOgU) ### Y Combinator 2.23M subscribers](http://www.youtube.com/@ycombinator) [Videos](http://www.youtube.com/channel/UCcefcZRL2oaA_uBNeo5UOWg/videos)[About](http://www.youtube.com/channel/UCcefcZRL2oaA_uBNeo5UOWg/about) Show less [](http://www.youtube.com/watch?v=JNyuX1zoOgU) # Demis Hassabis: Agents, AGI & The Next Big Scientific Breakthrough 50,272 views Apr 29, 2026 1.6K Share Save Download Download ## 90 Comments Sort comments Sort by [Top Show featured comments](http://www.youtube.com/watch?v=JNyuX1zoOgU)[Newest Show recent comments, including potential spam](http://www.youtube.com/watch?v=JNyuX1zoOgU) ![Image 17: Default profile photo](https://yt3.ggpht.com/a/default-user=s48-c-k-c0x00ffffff-no-rj) Add a comment... ![Image 18](https://yt3.ggpht.com/ytc/AIdro_n59z7waU3MSih5xNLFsCaGi91ZO-PKUAHYaYctXATy6kc=s88-c-k-c0x00ffffff-no-rj) ### [@cyberdudecyber](http://www.youtube.com/@cyberdudecyber) [19 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=Ugz9p_alLv5NjhXJIpF4AaABAg) Bro went from chess prodigy to game designer to neuroscientist to Nobel Prize winner to solve intelligence, create AGI, cure biology like a weekend to-do list. Some people really don’t know how to chill. Show less Read more Like 149 Dislike ![Image 19](https://yt3.ggpht.com/dGyATx87Fp_s1nZvnupUFSnMqbAPZ6nqRby9Esk1m6YE41iBq-9Z8iGoIgHTCT9SiDBUpP2V=s88-c-k-c0x00ffffff-no-rj) ❤ by @ycombinator Reply 13 replies Hide replies 13 replies ![Image 20](https://yt3.ggpht.com/MxnYZGTx29T089gM0G2dMNkYomwEA7GP7xISWxRLyUs_zJSW2UfTSDWlz1n437wbyNsIEaI7Xw=s88-c-k-c0x00ffffff-no-rj) ### [@bearonionlol](http://www.youtube.com/@bearonionlol) [15 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=UgwSUNrFrwz7OjxOw914AaABAg) Demis is arguably the most influential person of this decade Show less Read more Like 29 Dislike Reply ![Image 21](https://yt3.ggpht.com/r1TINjMJWOmTNmatc31wvCpu4ba371Oo9fP8C7iXSIA3eYR5LD3TSAowBrLOn_Q2rb8DTl6cTQ=s88-c-k-c0x00ffffff-no-rj) ### [@KenScott-bg7qj](http://www.youtube.com/@KenScott-bg7qj) [17 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=UgyN5zlDo5IU7RaQK254AaABAg) In Demis We Trust. Show less Read more Like 26 Dislike Reply 1 reply Hide replies 1 reply ![Image 22](https://yt3.ggpht.com/k6qZ3iKUgTpfXvZIlS6_cy3_cFfbJfDvLx1tdi21x0s-w11KFU8sE6SpZ7J_WmOIWLjrEOndYg=s88-c-k-c0x00ffffff-no-rj) ### [@amanmsiddiqui](http://www.youtube.com/@amanmsiddiqui) [17 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=UgyHKlBVXEEF-mbBC1d4AaABAg) We love Demis. Biggest takeaway from this talk: work on hard problems & AGI 2030. Show less Read more Like 19 Dislike Reply ![Image 23](https://yt3.ggpht.com/H9-Qc_Ybg4-Id3UsFgSQnahdfmRwmE2jKVbj8w-gSoPGTeQ1tdGDrzVKWFlAuY6L-zUVwsI4Jw=s88-c-k-c0x00ffffff-no-rj) ### [@eeko_systems](http://www.youtube.com/@eeko_systems) [16 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=UgxL4CPj-H07D9Gwzo94AaABAg) Demis is easily one of the most import people in the world now Keep this man safe at all costs Show less Read more Like 16 Dislike Reply ![Image 24](https://yt3.ggpht.com/ytc/AIdro_l6QcgF8Hy2A5WTq-BEouHKu4ZddK1f66sy6dT4Gjw=s88-c-k-c0x00ffffff-no-rj) ### [@johnk7025](http://www.youtube.com/@johnk7025) [16 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=UgzW5lyIGlY7ChVgv0t4AaABAg) demis ur the real agi Show less Read more Like 17 Dislike Reply 1 reply Hide replies 1 reply ![Image 25](https://yt3.ggpht.com/y0tGI_0DfxWzeGEZ0wh7syBLL_QTDh2zlrERQVEFiZoxmKBkbknlp32PrB_f28jBovxeR6Hd3rg=s88-c-k-c0x00ffffff-no-rj) ### [@CorranovoSolutions](http://www.youtube.com/@CorranovoSolutions) [8 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=UgxcLQ5N2lAvO7Saw0J4AaABAg) Feels like we’re still in the ‘duct tape’ phase. There's lots of potential, but the real advantage is how you use it, not just having access. Show less Read more Like 2 Dislike Reply ![Image 26](http://www.youtube.com/watch?v=JNyuX1zoOgU) ### [@pedrodpadua](http://www.youtube.com/@pedrodpadua) [3 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=Ugzvd9Lsc2mdIZCeo7V4AaABAg) Demis Hasabis is my role model. If there is someone that I look up to, it’s him Show less Read more Like 1 Dislike Reply ![Image 27](http://www.youtube.com/watch?v=JNyuX1zoOgU) ### [@wwondertwin](http://www.youtube.com/@wwondertwin) [15 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=UgwOhi9jEsiAbySH3XB4AaABAg) Demis Hassabis unable to pull that deeper reasoning out of Gemini just proves that it's always a PEBCAK situation. Show less Read more Like 3 Dislike Reply ![Image 28](http://www.youtube.com/watch?v=JNyuX1zoOgU) ### [@djg4653](http://www.youtube.com/@djg4653) [18 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=UgzQO73_0B6oS8r-1J14AaABAg) Thanks for keeping us informed Demis Show less Read more Like 4 Dislike Reply ![Image 29](http://www.youtube.com/watch?v=JNyuX1zoOgU) ### [@krissn8111](http://www.youtube.com/@krissn8111) [12 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=Ugxh4ZfWl7WNsqzGz214AaABAg) Happy to hear Sir Demis Hassabis. He always deliver great insights if you listen to him. Show less Read more Like 1 Dislike Reply ![Image 30](http://www.youtube.com/watch?v=JNyuX1zoOgU) ### [@sullyguy395](http://www.youtube.com/@sullyguy395) [16 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=UgzqQOffZOs1HlUJW1N4AaABAg) I’m no expert by any means but I’ve been following AI (and other tangentially related fields) more and more closely and I think a lot of people think AI as a field is at the exact same point it was which ChatGPT 3.5 but just scaled up. Scaling does offer lots of continuing surprising emergent benefits for reasons we are only beginning to understand and it will continue to do so. But the papers being published, the avenues of research being pursued, the discoveries being made are pretty mind blowing. People who think AI can only be what they saw a few years ago or even what they see now are in for a surprise. Show less Read more Like 3 Dislike Reply ![Image 31](http://www.youtube.com/watch?v=JNyuX1zoOgU) ### [@Sha-g8x2f](http://www.youtube.com/@Sha-g8x2f) [9 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=UgzQTCFhSIDBKeZfKfV4AaABAg) I see a Demis video I immediately watch it !! Show less Read more Like Dislike Reply ![Image 32](http://www.youtube.com/watch?v=JNyuX1zoOgU) ### [@danielatrotter3026](http://www.youtube.com/@danielatrotter3026) [9 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=UgzhyOA9vKGzauIVypd4AaABAg) It’s impossible not to love Demis. Show less Read more Like Dislike Reply ![Image 33](http://www.youtube.com/watch?v=JNyuX1zoOgU) ### [@MusicForHourss](http://www.youtube.com/@MusicForHourss) [18 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=UgwFZKBtdJB01apyhIB4AaABAg) Still trying to load garrysworld Show less Read more Like 6 Dislike Reply 1 reply Hide replies 1 reply ![Image 34](http://www.youtube.com/watch?v=JNyuX1zoOgU) ### [@douglasalvaradocorrales](http://www.youtube.com/@douglasalvaradocorrales) [16 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=UgzUYbE6Csux9Ifw24R4AaABAg) best [40:56](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=2456s) minutes of today, thanx for sharing ![Image 35: medal-yellow-first-red](http://www.youtube.com/watch?v=JNyuX1zoOgU) Show less Read more Like 2 Dislike Reply ![Image 36](http://www.youtube.com/watch?v=JNyuX1zoOgU) ### [@entreprenerd1963](http://www.youtube.com/@entreprenerd1963) [15 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=UgzDpBuARdtxtSz7bQp4AaABAg&pp=0gcJCSIANpG00pGi) I think we do have continual learning via the continual backpropagation algorithm, albeit by increasing costs in the range of 10x to 100x. However, the lesson of the Tay chatbot is clear: no frontier model company is going to allow distributed real-time training via user input streams.of its centralized frontier model. Show less Read more Like 2 Dislike Reply ![Image 37](http://www.youtube.com/watch?v=JNyuX1zoOgU) ### [@Elevanix_official1](http://www.youtube.com/@Elevanix_official1) [13 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=Ugz-usJk5rjvXpU5wrN4AaABAg) I am inspired by the questions Garry comes up with. I still don't know about people judging the quality of YC for no reason, just to be on a side that is easy to join, maybe Show less Read more Like Dislike Reply ![Image 38](http://www.youtube.com/watch?v=JNyuX1zoOgU) ### [@Hedgehogmustache](http://www.youtube.com/@Hedgehogmustache) [13 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=UgwwChIya1fxQ9x1IZ54AaABAg) Narrator did a great job interviewing Demis! Show less Read more Like Dislike Reply ![Image 39](http://www.youtube.com/watch?v=JNyuX1zoOgU) ### [@dexmoe](http://www.youtube.com/@dexmoe) [5 hours ago](http://www.youtube.com/watch?v=JNyuX1zoOgU&lc=UgyeAnTwsXMzuAeyx914AaABAg) the lighting on Sir Demis' head is _ Show less Read more Like Dislike Reply ## Comments 90 [Top Show featured comments](http://www.youtube.com/watch?v=JNyuX1zoOgU)[Newest Show recent comments, including potential spam](http://www.youtube.com/watch?v=JNyuX1zoOgU) ## In this video Chapters Transcript ## Chapters [![Image 40](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Intro #### Intro 0:00](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### [Intro](http://www.youtube.com/watch?v=JNyuX1zoOgU) 0:00 [![Image 41](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Demis Hassabis: From Chess Prodigy to DeepMind #### Demis Hassabis: From Chess Prodigy to DeepMind 0:46](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=46s) #### [Demis Hassabis: From Chess Prodigy to DeepMind](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=46s) 0:46 [![Image 42](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### What’s Missing Before We Get To AGI? #### What’s Missing Before We Get To AGI? 1:48](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=108s) #### [What’s Missing Before We Get To AGI?](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=108s) 1:48 [![Image 43](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Why Memory Is Still Unsolved #### Why Memory Is Still Unsolved 3:36](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=216s) #### [Why Memory Is Still Unsolved](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=216s) 3:36 [![Image 44](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### How AlphaGo Shaped Gemini #### How AlphaGo Shaped Gemini 6:14](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=374s) #### [How AlphaGo Shaped Gemini](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=374s) 6:14 [![Image 45](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Why Smaller Models Are Getting So Powerful #### Why Smaller Models Are Getting So Powerful 8:06](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=486s) #### [Why Smaller Models Are Getting So Powerful](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=486s) 8:06 [![Image 46](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### The 1000x Engineer #### The 1000x Engineer 10:46](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=646s) #### [The 1000x Engineer](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=646s) 10:46 [![Image 47](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Continual Learning and the Future of Agents #### Continual Learning and the Future of Agents 12:40](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=760s) #### [Continual Learning and the Future of Agents](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=760s) 12:40 [![Image 48](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Why AI Still Fails at Basic Reasoning #### Why AI Still Fails at Basic Reasoning 13:32](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=812s) #### [Why AI Still Fails at Basic Reasoning](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=812s) 13:32 [![Image 49](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Are Agents Overhyped or Just Getting Started? #### Are Agents Overhyped or Just Getting Started? 15:33](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=933s) #### [Are Agents Overhyped or Just Getting Started?](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=933s) 15:33 [![Image 50](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Can AI Become Truly Creative? #### Can AI Become Truly Creative? 18:31](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1111s) #### [Can AI Become Truly Creative?](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1111s) 18:31 [![Image 51](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Open Models, Gemma, and Local AI #### Open Models, Gemma, and Local AI 20:26](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1226s) #### [Open Models, Gemma, and Local AI](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1226s) 20:26 [![Image 52](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Why Gemini Was Built Multimodal #### Why Gemini Was Built Multimodal 22:26](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1346s) #### [Why Gemini Was Built Multimodal](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1346s) 22:26 [![Image 53](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### What Happens When Inference Gets Cheap? #### What Happens When Inference Gets Cheap? 24:08](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1448s) #### [What Happens When Inference Gets Cheap?](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1448s) 24:08 [![Image 54](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### From AlphaFold to the Virtual Cells #### From AlphaFold to the Virtual Cells 25:24](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1524s) #### [From AlphaFold to the Virtual Cells](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1524s) 25:24 [![Image 55](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### AI as the Ultimate Tool for Science #### AI as the Ultimate Tool for Science 28:24](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1704s) #### [AI as the Ultimate Tool for Science](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1704s) 28:24 [![Image 56](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Advice for Founders #### Advice for Founders 30:43](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1843s) #### [Advice for Founders](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1843s) 30:43 [![Image 57](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### The AlphaFold Breakthrough Pattern #### The AlphaFold Breakthrough Pattern 33:30](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=2010s) #### [The AlphaFold Breakthrough Pattern](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=2010s) 33:30 [![Image 58](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Can AI Make Real Scientific Discoveries? #### Can AI Make Real Scientific Discoveries? 35:20](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=2120s) #### [Can AI Make Real Scientific Discoveries?](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=2120s) 35:20 [![Image 59](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### What to Build Before AGI Arrives #### What to Build Before AGI Arrives 37:59](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=2279s) #### [What to Build Before AGI Arrives](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=2279s) 37:59 Sync to video time ## Description Demis Hassabis: Agents, AGI & The Next Big Scientific Breakthrough 1.6K Likes 50,272 Views 19h Ago Demis Hassabis has had one of the most extraordinary careers in tech. He started as a chess prodigy and video game designer at 17 before getting a PhD in neuroscience and going on to found DeepMind. His lab cracked Go, solved protein structure prediction with AlphaFold, and then gave it away free to every scientist on earth. That work won him the 2024 Nobel Prize in Chemistry. Today he leads Google DeepMind, pushing toward the same goal he set as a teenager: AGI. On this special live episode of How to Build the Future, he sat down with YC's Garry Tan to talk about what still needs to happen to get us to AGI, his advice for founders on how to stay ahead of the curve and what the next big scientific breakthroughs might be. Chapters: [00:00](http://www.youtube.com/watch?v=JNyuX1zoOgU) — Intro [00:46](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=46s) — Demis Hassabis: From Chess Prodigy to DeepMind [01:48](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=108s) — What’s Missing Before We Get To AGI? [03:36](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=216s) — Why Memory Is Still Unsolved [06:14](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=374s) — How AlphaGo Shaped Gemini [08:06](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=486s) — Why Smaller Models Are Getting So Powerful [10:46](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=646s) — The 1000x Engineer [12:40](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=760s) — Continual Learning and the Future of Agents [13:32](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=812s) — Why AI Still Fails at Basic Reasoning [15:33](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=933s) — Are Agents Overhyped or Just Getting Started? [18:31](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1111s) — Can AI Become Truly Creative? [20:26](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1226s) — Open Models, Gemma, and Local AI [22:26](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1346s) — Why Gemini Was Built Multimodal [24:08](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1448s) — What Happens When Inference Gets Cheap? [25:24](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1524s) — From AlphaFold to the Virtual Cells [28:24](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1704s) — AI as the Ultimate Tool for Science [30:43](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=1843s) — Advice for Founders [33:30](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=2010s) — The AlphaFold Breakthrough Pattern [35:20](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=2120s) — Can AI Make Real Scientific Discoveries? [37:59](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=2279s) — What to Build Before AGI Arrives Apply to Y Combinator: [https://www.ycombinator.com/apply](https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbTVfTDVQZ0JVSC1yR1FTb0NvUkNHcFZiaTl4UXxBQ3Jtc0ttQW9tSTE5YWhxeEI4WG5DSksyczNZTEM3VWxWWTVUY0NJbGV4U3pIeVU4U3FXZUxxSndhYmJEQmdLcFpGSzNRcmRUVXZpWE5yLXpfQS1zRHViVFk0VjJubGxuSzBvLWRrSjcyZldHRGR6N1lydS1jYw&q=https%3A%2F%2Fwww.ycombinator.com%2Fapply&v=JNyuX1zoOgU) Work at a startup: [https://www.ycombinator.com/jobs](https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbHUtOEtDTFA2dVdnTnRCTnZnaGo0b3p4QmpzUXxBQ3Jtc0ttWmpmUEU0SDdXSGt6MElYclhwaTY1RzRmb19vdmhyZUtoU04wcDZVOGRXRGNScjFpYmtBX3hzWFI0UGEyek9LWEYyV09BMlhOMUcyNWxMSjItRFBzb0xHNGs3ekpkZzAyY1k2NHd4MC1ZYlVvREFMMA&q=https%3A%2F%2Fwww.ycombinator.com%2Fjobs&v=JNyuX1zoOgU)…...more ...more Show less How this was made Auto-dubbed Audio tracks for some languages were automatically generated. [Learn more](http://support.google.com/youtube/answer/15569972?hl=en) ## Chapters View all [![Image 60](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Intro #### Intro 0:00](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### [Intro](http://www.youtube.com/watch?v=JNyuX1zoOgU) 0:00 [![Image 61](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Demis Hassabis: From Chess Prodigy to DeepMind #### Demis Hassabis: From Chess Prodigy to DeepMind 0:46](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=46s) #### [Demis Hassabis: From Chess Prodigy to DeepMind](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=46s) 0:46 [![Image 62](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### What’s Missing Before We Get To AGI? #### What’s Missing Before We Get To AGI? 1:48](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=108s) #### [What’s Missing Before We Get To AGI?](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=108s) 1:48 [![Image 63](http://www.youtube.com/watch?v=JNyuX1zoOgU) #### Why Memory Is Still Unsolved #### Why Memory Is Still Unsolved 3:36](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=216s&pp=0gcJCREDDuyUWbzu) #### [Why Memory Is Still Unsolved](http://www.youtube.com/watch?v=JNyuX1zoOgU&t=216s&pp=0gcJCREDDuyUWbzu) 3:36 Transcript Follow along using the transcript. Show transcript [![Image 64](http://www.youtube.com/watch?v=JNyuX1zoOgU) ### Y Combinator 2.23M subscribers](http://www.youtube.com/@ycombinator) [Videos](http://www.youtube.com/channel/UCcefcZRL2oaA_uBNeo5UOWg/videos)[About](http://www.youtube.com/channel/UCcefcZRL2oaA_uBNeo5UOWg/about) ## Transcript NaN / NaN [![Image 65](https://i.ytimg.com/vi/AFpeWo1GTeg/hqdefault.jpg?sqp=-oaymwEmCKgBEF5IWvKriqkDGQgBFQAAiEIYAdgBAeIBCggYEAIYBjgBQAE=&rs=AOn4CLDlf3atwgHS743ZTvHpzCZa2UYpVA) 26:52](http://www.youtube.com/watch?v=AFpeWo1GTeg&pp=ugUEEgJlbg%3D%3D) ![Image 66](http://www.youtube.com/watch?v=JNyuX1zoOgU) ### [Demis Hassabis: We're Three Quarters of the Way to AGI](http://www.youtube.com/watch?v=AFpeWo1GTeg&pp=ugUEEgJlbg%3D%3D) Sequoia Capital 46K views • 18 hours ago New [![Image 67](https://i.ytimg.com/vi/96jN2OCOfLs/hqdefault.jpg?sqp=-oaymwEmCKgBEF5IWvKriqkDGQgBFQAAiEIYAdgBAeIBCggYEAIYBjgBQAE=&rs=AOn4CLBZdp1cX62GE_0F_7p8NNyecd0HIQ) 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