The Download: GLP-1s and eating disorders, self-aware cities, and forever chemicals

TL;DR · AI 摘要
文章涵盖GLP-1药物与饮食失调关联、自我意识城市虚构故事及PFAS化学清理进展,但对工程师实践影响有限。
核心要点
- GLP-1减肥药可能加剧饮食失调问题,需警惕临床风险。
- Binance遭受63亿美元加密货币盗窃,凸显安全漏洞。
- PFAS化学清理技术尚处早期,需优先从水系统中去除污染物。
结构提纲
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思维导图
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- The Download专题
- 医疗科技
- GLP-1药物风险
- 饮食失调数据
- 城市科技
- 智能城市伦理
- 直接民主挑战
- 环境科技
- PFAS污染治理
- 水系统净化
- 安全事件
- Binance黑客案
- 加密货币损失
金句 / Highlights
值得收藏与分享的关键句。
GLP-1s could make things worse—new report shows 71% rise in eating disorders since 1990.
Binance hack affected $6.3 billion assets, with North Korea suspected by analysts.
PFAS removal from water systems is critical to prevent chemical buildup in environment.
The Download: GLP-1s and eating disorders, self-aware cities, and forever chemicals | MIT Technology Review
The Download
The Download: GLP-1s and eating disorders, self-aware cities, and forever chemicals
Plus: Binance has suffered the biggest crypto hack in history.
By
- Thomas Macaulay archive page
October 30, 2026
This is today's edition of The Download , our weekday newsletter that provides a daily dose of what's going on in the world of technology.
Eating disorders are on the rise. GLP-1s could make things worse.
GLP-1 weight-loss drugs are one of the biggest biotech breakthroughs of the last decade. But to some clinicians, they can represent something sinister—a potential trigger for eating disorders.
A new report suggests the global incidence of anorexia nervosa and bulimia nervosa shot up by 71% between 1990 and 2023. And clinicians are already seeing GLP-1s exacerbate the issue.
Here’s how they could make an already growing problem worse .
—Jessica Hamzelou
This story is from The Checkup, our weekly biotech newsletter. Sign up to receive it in your inbox every Thursday.
Love is infrastructure
—“Love is Infrastructure” is a short fictional story by Charlie Jane Anders, author of a forthcoming novel titled Good Things Are Coming Your Way .
Mainspring and St. Barnabas are two neighboring cities with different personalities. They’ve never particularly liked each other, but that changes when both develop minds of their own, shaped by the votes of their residents.
As the cities begin to fall for each other, a third city enters the picture. Turnbull promises Mainspring a more efficient future, but its vision of urban life comes with a troubling price.
Read the full short story about self-aware cities, direct democracy, and a steamy romance.
This story is from the latest edition of our print magazine . Subscribe now to get every issue as soon as it lands.
Are we there yet? Cleaning up PFAS
Used for decades in everything from nonstick pans to firefighting foams, PFAS, or “forever chemicals,” are linked to increased risks of fertility challenges, developmental delays, cancer, and reduced immune response.
Scrubbing PFAS-contaminated soil could eliminate a list of woes for people and planet. The concept is still in its infancy, but we can limit their buildup by pulling the chemicals out of water systems.
Find out how close we are to ridding the world of forever chemicals .
—Sara Kiley Watson
This story is part of “Are we there yet?” , our series that takes stock of six technologies that have long promised to change the world—and scores them on a progress meter. We’re exploring each one in The Download, so stay tuned, and subscribe to read the rest of the stories in our new Impossible issue .
The must-reads
I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology.
1 Binance has suffered the biggest crypto hack in history The exchange says $6.3 billion in assets were affected. ( BBC ) + Analysts blamed the hack on North Korea. ( Guardian ) + The Bitcoin stolen will likely never be recovered. ( Bloomberg $) + Binance has suspended all deposits and withdrawals. ( NBC News ) + How a pastor’s crypto scheme lost investors millions. ( MIT Technology Review )
2 Nvidia’s Jensen Huang was targeted by an alleged Chinese spy The suspect is an executive at a Singapore data center firm. ( NYT $) + US intelligence believes she cultivated ties with Huang. ( Guardian ) + Her company was investigated over alleged chip diversion. ( CNBC ) + Nvidia says their dealings were “normal.” ( Bloomberg $)
3 Alphabet just shed $500 billion in market value The record loss is due to AI taking a bite out of its search profits. ( CNBC ) + Amazon and Intel further a further fall in tech stocks. ( Bloomberg $) + Hyperscalers are making a trillion-dollar gamble. ( MIT Technology Review )
4 The Pentagon suspects freezers at military bases were hacked The malfunctions spoiled food. ( Reuters $) + They may be linked to similar hacks in French supermarkets . ( Gizmodo )
5 The US midterms could reshape the future of American science A Democratic Congress could curb Trump’s science cuts. ( Nature ) + Trump has already dealt big blows to science. ( MIT Technology Review )
6 Data centers are set to send US climate pollution skyrocketing Gas plants could push power-sector emissions up 42% by 2030.( Verge ) + Europe’s data centre workers face dangerous conditions. ( Guardian )
7 SpaceX is pulling away from NASA The company is prioritising Starlink and AI. ( Ars Technica ) + But Cape Canaveral is busier than during the space race. ( Axios )
8 Battery makers are finding a new market in the US They’re pivoting from EVs to grid storage. ( WSJ $) + Batteries just broke another record in the US. ( MIT Technology Review )
9 A humanist has received a religious exemption from using AI at work He argued that using it undermined human flourishing. ( Gizmodo )
10 Psychics are fighting back against computerized clairvoyance Human practitioners say chatbots lack the divine touch. ( Guardian )
Quote of the day
“Rizz is in more and more demand because it's something that only people have.”
—Steven Strogatz, a mathematics professor at Cornell University, tells Business Insider that personal appeal will become more valuable as AI increasingly takes over intellectual work.
One more thing
#### The Bay Area’s animal welfare movement wants to recruit AI
In early February, animal welfare advocates and AI researchers arrived in stocking feet at Mox, a shoes-free coworking space in San Francisco. They gathered to discuss a provocative idea: if artificial general intelligence is on the horizon, could it prevent animal suffering?
Some brainstormed using custom agents in advocacy work, while others pitched cultivating meat with AI tools. But the real talk of the event was a flood of funding they expect will soon flow to animal welfare charities, not from individual megadonors, but from AI lab employees.
Some attendees also probed an even more controversial idea: AI may develop the capacity to suffer, which could constitute a moral catastrophe. We investigated why their ideas are gaining momentum—and sparking controversy.
—Michelle Kim & Grace Huckins
We can still have nice things
A place for comfort, fun, and distraction to brighten up your day. Today, it’s a Halloween special. (Got any ideas? Drop me a line .)
+ Meet the “Picasso of Pumpkin Carvers” , bringing artistry to a Halloween tradition. + Mashup maestro Bill McClintock's Ghostmashers is the ideal soundtrack for your All Hallows' Eve party. + Want to give someone a proper fright this year? The pros behind America's haunted attractions have tips . + This incredible Halloween light show combines 210 drones, fire, lasers, projection, fountains, and the Beastie Boys.
Deep Dive
The Download
The Download: why AI’s latest breakthroughs and fears may be more hype than reality
Plus: 22 nations have called for a new global body to oversee AI.
The Download: weight-loss drugs slowing aging and carbon dioxide batteries
Plus: OpenAI has released 377 new math findings, further rattling the field.
The Download: 10 climate tech companies to watch
Plus: Musk’s new Pentagon role has raised conflict-of-interest fears.
The Download: AI’s trillion-dollar gamble and OpenAI’s biology data bid
Plus: Nvidia and Meta CEOs have rejected calls for a coordinated AI slowdown.
Stay connected
Illustration by Rose Wong
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